diff --git a/core/iwasm/compilation/aot_compiler.c b/core/iwasm/compilation/aot_compiler.c
index 81ad9b7a3..9740cd0d1 100644
--- a/core/iwasm/compilation/aot_compiler.c
+++ b/core/iwasm/compilation/aot_compiler.c
@@ -966,7 +966,9 @@ aot_compile_func(AOTCompContext *comp_ctx, uint32 func_index)
         location = dwarf_gen_location(
             comp_ctx, func_ctx,
             (frame_ip - 1) - comp_ctx->comp_data->wasm_module->buf_code);
-        LLVMSetCurrentDebugLocation2(comp_ctx->builder, location);
+        if (location != NULL) {
+            LLVMSetCurrentDebugLocation2(comp_ctx->builder, location);
+        }
 #endif
 
         switch (opcode) {
diff --git a/core/iwasm/compilation/aot_emit_control.c b/core/iwasm/compilation/aot_emit_control.c
index 8b24bcab8..4e28babc3 100644
--- a/core/iwasm/compilation/aot_emit_control.c
+++ b/core/iwasm/compilation/aot_emit_control.c
@@ -374,7 +374,9 @@ handle_next_reachable_block(AOTCompContext *comp_ctx, AOTFuncContext *func_ctx,
                 goto fail;
             }
 #if WASM_ENABLE_DEBUG_AOT != 0
-            LLVMInstructionSetDebugLoc(ret, return_location);
+            if (return_location != NULL) {
+                LLVMInstructionSetDebugLoc(ret, return_location);
+            }
 #endif
         }
         else {
@@ -383,7 +385,9 @@ handle_next_reachable_block(AOTCompContext *comp_ctx, AOTFuncContext *func_ctx,
                 goto fail;
             }
 #if WASM_ENABLE_DEBUG_AOT != 0
-            LLVMInstructionSetDebugLoc(ret, return_location);
+            if (return_location != NULL) {
+                LLVMInstructionSetDebugLoc(ret, return_location);
+            }
 #endif
         }
     }
diff --git a/core/iwasm/compilation/debug/dwarf_extractor.cpp b/core/iwasm/compilation/debug/dwarf_extractor.cpp
index 06618ad70..da33fc432 100644
--- a/core/iwasm/compilation/debug/dwarf_extractor.cpp
+++ b/core/iwasm/compilation/debug/dwarf_extractor.cpp
@@ -491,6 +491,8 @@ dwarf_gen_location(const AOTCompContext *comp_ctx,
     dwarf_extractor *extractor;
     AOTFunc *func = func_ctx->aot_func;
 
+    if (func_ctx->debug_func == NULL)
+        return NULL;
     if (!(extractor = TO_EXTACTOR(comp_ctx->comp_data->extractor)))
         return NULL;