diff --git a/core/iwasm/compilation/aot_compiler.c b/core/iwasm/compilation/aot_compiler.c
index 82f70ca3d..5d9664ee8 100644
--- a/core/iwasm/compilation/aot_compiler.c
+++ b/core/iwasm/compilation/aot_compiler.c
@@ -1316,6 +1316,13 @@ aot_compile_func(AOTCompContext *comp_ctx, uint32 func_index)
                     return false;
                 break;
 
+#if WASM_ENABLE_SIMD != 0
+            case WASM_OP_SELECT_128:
+                if (!aot_compile_op_select(comp_ctx, func_ctx, true))
+                    return false;
+                break;
+#endif
+
 #if WASM_ENABLE_REF_TYPES != 0 || WASM_ENABLE_GC != 0
             case WASM_OP_SELECT_T:
             {
diff --git a/core/iwasm/interpreter/wasm_interp_fast.c b/core/iwasm/interpreter/wasm_interp_fast.c
index f33ad60e3..e0e5073e6 100644
--- a/core/iwasm/interpreter/wasm_interp_fast.c
+++ b/core/iwasm/interpreter/wasm_interp_fast.c
@@ -1888,6 +1888,28 @@ wasm_interp_call_func_bytecode(WASMModuleInstance *module,
                 }
                 HANDLE_OP_END();
             }
+#if WASM_ENABLE_JIT != 0 \
+    || WASM_ENABLE_FAST_INTERP != 0 && WASM_ENABLE_SIMD != 0
+            HANDLE_OP(WASM_OP_SELECT_128)
+            {
+                cond = frame_lp[GET_OFFSET()];
+                addr1 = GET_OFFSET();
+                addr2 = GET_OFFSET();
+                addr_ret = GET_OFFSET();
+
+                if (!cond) {
+                    if (addr_ret != addr1)
+                        PUT_V128_TO_ADDR(frame_lp + addr_ret,
+                                         GET_V128_FROM_ADDR(frame_lp + addr1));
+                }
+                else {
+                    if (addr_ret != addr2)
+                        PUT_V128_TO_ADDR(frame_lp + addr_ret,
+                                         GET_V128_FROM_ADDR(frame_lp + addr2));
+                }
+                HANDLE_OP_END();
+            }
+#endif
 
 #if WASM_ENABLE_GC != 0
             HANDLE_OP(WASM_OP_SELECT_T)
diff --git a/core/iwasm/interpreter/wasm_loader.c b/core/iwasm/interpreter/wasm_loader.c
index fc68e5966..f6f8893a2 100644
--- a/core/iwasm/interpreter/wasm_loader.c
+++ b/core/iwasm/interpreter/wasm_loader.c
@@ -7295,6 +7295,9 @@ wasm_loader_find_block_addr(WASMExecEnv *exec_env, BlockAddr *block_addr_cache,
             case WASM_OP_SELECT:
             case WASM_OP_DROP_64:
             case WASM_OP_SELECT_64:
+#if WASM_ENABLE_FAST_INTERP != 0 && WASM_ENABLE_SIMD != 0
+            case WASM_OP_SELECT_128:
+#endif
                 break;
 
 #if WASM_ENABLE_REF_TYPES != 0 || WASM_ENABLE_GC != 0
@@ -12770,8 +12773,7 @@ re_scan:
                         case VALUE_TYPE_F64:
 #if WASM_ENABLE_FAST_INTERP == 0
                             *(p - 1) = WASM_OP_SELECT_64;
-#endif
-#if WASM_ENABLE_FAST_INTERP != 0
+#else
                             if (loader_ctx->p_code_compiled) {
                                 uint8 opcode_tmp = WASM_OP_SELECT_64;
 #if WASM_ENABLE_LABELS_AS_VALUES != 0
@@ -12779,8 +12781,7 @@ re_scan:
                                 *(void **)(p_code_compiled_tmp
                                            - sizeof(void *)) =
                                     handle_table[opcode_tmp];
-#else
-#if UINTPTR_MAX == UINT64_MAX
+#elif UINTPTR_MAX == UINT64_MAX
                                 /* emit int32 relative offset in 64-bit target
                                  */
                                 int32 offset =
@@ -12793,7 +12794,6 @@ re_scan:
                                 *(uint32 *)(p_code_compiled_tmp
                                             - sizeof(uint32)) =
                                     (uint32)(uintptr_t)handle_table[opcode_tmp];
-#endif
 #endif /* end of WASM_CPU_SUPPORTS_UNALIGNED_ADDR_ACCESS */
 #else  /* else of WASM_ENABLE_LABELS_AS_VALUES */
 #if WASM_CPU_SUPPORTS_UNALIGNED_ADDR_ACCESS != 0
@@ -12809,6 +12809,39 @@ re_scan:
 #if (WASM_ENABLE_WAMR_COMPILER != 0) || (WASM_ENABLE_JIT != 0) \
     || (WASM_ENABLE_FAST_INTERP != 0)
                         case VALUE_TYPE_V128:
+#if WASM_ENABLE_FAST_INTERP == 0
+                            *(p - 1) = WASM_OP_SELECT_128;
+#else
+                            if (loader_ctx->p_code_compiled) {
+                                uint8 opcode_tmp = WASM_OP_SELECT_128;
+#if WASM_ENABLE_LABELS_AS_VALUES != 0
+#if WASM_CPU_SUPPORTS_UNALIGNED_ADDR_ACCESS != 0
+                                *(void **)(p_code_compiled_tmp
+                                           - sizeof(void *)) =
+                                    handle_table[opcode_tmp];
+#elif UINTPTR_MAX == UINT64_MAX
+                                /* emit int32 relative offset in 64-bit target
+                                 */
+                                int32 offset =
+                                    (int32)((uint8 *)handle_table[opcode_tmp]
+                                            - (uint8 *)handle_table[0]);
+                                *(int32 *)(p_code_compiled_tmp
+                                           - sizeof(int32)) = offset;
+#else
+                                /* emit uint32 label address in 32-bit target */
+                                *(uint32 *)(p_code_compiled_tmp
+                                            - sizeof(uint32)) =
+                                    (uint32)(uintptr_t)handle_table[opcode_tmp];
+#endif /* end of WASM_CPU_SUPPORTS_UNALIGNED_ADDR_ACCESS */
+#else  /* else of WASM_ENABLE_LABELS_AS_VALUES */
+#if WASM_CPU_SUPPORTS_UNALIGNED_ADDR_ACCESS != 0
+                                *(p_code_compiled_tmp - 1) = opcode_tmp;
+#else
+                                *(p_code_compiled_tmp - 2) = opcode_tmp;
+#endif /* end of WASM_CPU_SUPPORTS_UNALIGNED_ADDR_ACCESS */
+#endif /* end of WASM_ENABLE_LABELS_AS_VALUES */
+                            }
+#endif /* end of WASM_ENABLE_FAST_INTERP */
                             break;
 #endif /* (WASM_ENABLE_WAMR_COMPILER != 0) || (WASM_ENABLE_JIT != 0) || \
           (WASM_ENABLE_FAST_INTERP != 0) */
@@ -12906,12 +12939,9 @@ re_scan:
                     uint8 opcode_tmp = WASM_OP_SELECT;
 
                     if (type == VALUE_TYPE_V128) {
-#if (WASM_ENABLE_SIMD == 0)                                        \
-    || ((WASM_ENABLE_WAMR_COMPILER == 0) && (WASM_ENABLE_JIT == 0) \
-        && (WASM_ENABLE_FAST_INTERP == 0))
-                        set_error_buf(error_buf, error_buf_size,
-                                      "SIMD v128 type isn't supported");
-                        goto fail;
+#if WASM_ENABLE_JIT != 0 \
+    || WASM_ENABLE_FAST_INTERP != 0 && WASM_ENABLE_SIMD != 0
+                        opcode_tmp = WASM_OP_SELECT_128;
 #endif
                     }
                     else {
diff --git a/core/iwasm/interpreter/wasm_opcode.h b/core/iwasm/interpreter/wasm_opcode.h
index 9660bb123..07e3d9f09 100644
--- a/core/iwasm/interpreter/wasm_opcode.h
+++ b/core/iwasm/interpreter/wasm_opcode.h
@@ -278,13 +278,14 @@ typedef enum WASMOpcode {
     DEBUG_OP_BREAK = 0xdc, /* debug break point */
 #endif
 
-#if WASM_ENABLE_JIT != 0 \
-    || WASM_ENABLE_FAST_INTERP != 0 && WASM_ENABLE_SIMD != 0
+#if WASM_ENABLE_JIT != 0 || WASM_ENABLE_FAST_INTERP != 0 \
+    || WASM_ENABLE_WAMR_COMPILER != 0 && WASM_ENABLE_SIMD != 0
     EXT_OP_SET_LOCAL_FAST_V128 = 0xdd,
     EXT_OP_TEE_LOCAL_FAST_V128 = 0xde,
     EXT_OP_COPY_STACK_TOP_V128 = 0xdf,
     WASM_OP_GET_GLOBAL_V128 = 0xe0,
     WASM_OP_SET_GLOBAL_V128 = 0xe1,
+    WASM_OP_SELECT_128 = 0xe2,
 #endif
 
     /* Post-MVP extend op prefix */
@@ -804,7 +805,8 @@ typedef enum WASMAtomicEXTOpcode {
         SET_GOTO_TABLE_ELEM(EXT_OP_TEE_LOCAL_FAST_V128), /* 0xde */ \
         SET_GOTO_TABLE_ELEM(EXT_OP_COPY_STACK_TOP_V128), /* 0xdf */ \
         SET_GOTO_TABLE_ELEM(WASM_OP_GET_GLOBAL_V128),    /* 0xe0 */ \
-        SET_GOTO_TABLE_ELEM(WASM_OP_SET_GLOBAL_V128),    /* 0xe1 */
+        SET_GOTO_TABLE_ELEM(WASM_OP_SET_GLOBAL_V128),    /* 0xe1 */ \
+        SET_GOTO_TABLE_ELEM(WASM_OP_SELECT_128),         /* 0xe2 */
 
 #else
 #define DEF_EXT_V128_HANDLE()